Chest Pain and Inflammation: A Story Where Hickam's Dictum Prevailed

      While Occam's razor refers to a single condition explaining a patient's clinical presentation, Hickam's dictum serves as the counterbalance to this phrase such that symptoms can be secondary to a variety of diagnoses. Here, we present a case of a patient whose presentation was due to the latter.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to The American Journal of Medicine
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Cremer PC
        • Kumar A
        • Kontzias A
        • et al.
        Complicated pericarditis: understanding risk factors and pathophysiology to inform imaging and treatment.
        J Am Coll Cardiol. 2016; 68: 2311-2328
        • Man BL
        • Mok CC
        Serositis related to systemic lupus erythematosus: prevalence and outcome.
        Lupus. 2005; 14: 822-826
        • Rosenbaum E
        • Krebs E
        • Cohen M
        • Tiliakos A
        • Derk CT
        The spectrum of clinical manifestations, outcome and treatment of pericardial tamponade in patients with systemic lupus erythematosus: a retrospective study and literature review.
        Lupus. 2009; 18: 608-612
        • Guindo J
        • Rodriguez de la Serna A
        • Ramió J
        • et al.
        Recurrent pericarditis relief with colchicine.
        Circulation. 1990; 82: 1117-1120
      1. Jandali B, Uthman I, Abbas O. Interstitial granulomatous dermatitis associated with systemic lupus erythematosus: case report and review of the literature. Lupus. 2016;25(2):209-213.

        • Hochberg MC
        Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus.
        Arthritis Rheum. 1997; 40: 1725
        • Petri M
        • Orbai AM
        • Alarcón GS
        • et al.
        Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus.
        Arthritis Rheum. 2012; 64: 2677-2686
        • Miner J
        • Kim AHJ
        Cardiac manifestations of systemic lupus erythematosus.
        Rheum Dis Clin North Am. 2014; 40: 51-60
        • Jouhikainen T
        • Pohjola-Sintonen S
        • Stephansson E
        Lupus anticoagulant and cardiac manifestations in systemic lupus erythematosus.
        Lupus. 1994; 3: 167-172
        • Barile-Fabris L
        • Hernández-Cabrera MF
        • Barragan-Garfias JA
        Vasculitis in systemic lupus erythematosus.
        Curr Rheumatol Rep. 2014; 16: 440
        • Asanuma Y
        • Oeser A
        • Shintani AK
        • et al.
        Premature coronary-artery atherosclerosis in systemic lupus erythematosus.
        N Engl J Med. 2003; 349: 2407-2415
        • Roman MJ
        • Shanker BA
        • Davis A
        • et al.
        Prevalence and correlates of accelerated atherosclerosis in systemic lupus erythematosus.
        N Engl J Med. 2003; 349: 2399-2406
        • Schoenfeld SR
        • Kasturi S
        • Costenbader KH
        The epidemiology of atherosclerotic cardiovascular disease among patients with SLE: a systematic review.
        Semin Arthritis Rheum. 2013; 43: 77-95
        • Espínola-Zavaleta N
        • Vargas-Barrón J
        • Colmenares-Galvis T
        • et al.
        Echocardiographic evaluation of patients with primary antiphospholipid syndrome.
        Am Heart J. 1999; 137: 973-978