A 34-year-old man presented with history of intermittent throbbing frontal headache
of 3 months duration. A week prior to presentation he had an episode of severe headache
associated with nausea and vomiting, requiring hospitalization and parenteral analgesics.
Magnetic resonance imaging (MRI) of the brain done detected a pituitary macroadenoma
and he was referred to the Endocrinology Department for clearance prior to surgery.
On questioning he also gave history of cold intolerance, weight gain despite poor
appetite, easy fatigability, and hoarseness of voice for the past year. He had a puffy
face and spoke in a hoarse voice. He also had sinus bradycardia, diastolic hypertension,
non-pitting pedal edema, and delayed relaxation of deep tendon jerks. The thyroid
gland was not palpable.
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References
- Pituitary hyperplasia.Hormones (Athens). 2003; 2: 149-158
- Pituitary hyperplasia: case series and literature review of an under-recognised and heterogeneous condition.Endocrinol Diabetes Metab Case Rep. 2015; 2015150017
- Pituitary hyperplasia from primary hypothyroidism.N Engl J Med. 2019; 380: e9
- Pituitary enlargement in patients with primary hypothyroidism.Endocr Pract. 2006; 12: 29-34
- Serum prolactin levels in untreated primary hypothyroidism.Am J Med. 1978; 64: 782-787
- MRI in the differential diagnosis of a sellar mass.Clin Radiol. 2003; 58: 20-31
Article Info
Publication History
Published online: January 30, 2022
Robert G. Stern, MD, Section EditorFootnotes
Funding: None.
Conflicts of Interest: None.
Authorship: VSS wrote the manuscript and managed the patient, AC edited the manuscript and conducted radiological study. Both authors had access to the data and a role in writing the manuscript.
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Copyright
© 2022 Elsevier Inc. All rights reserved.
