The Great Imitator: Primary Syphilis Clinically Mimicking Oral Squamous Cell Carcinoma

      A 32-year-old Italian man who has sex with men (MSM) presented to our clinic with a 10-day history of a solitary, painless, rapidly enlarging nodule on the dorsum of the tongue, which did not hurt him and did not interfere with eating or drinking. The patient reported flu-like symptoms, in particular fever, night sweats, myalgia, and generalized weakness. The patient had a human immunodeficiency virus (HIV) screening test 3 months earlier, which came back negative.
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