The patient is a 71 year old male with no past medical history who was admitted for
back pain. Investigations confirmed spondylodiscitis of the L4 and L5 vertebrae with
methicillin-resistant Staphylococcus Aureus (MRSA) bacteremia. He was started on intravenous
(IV) vancomycin and underwent posterior L4 – L5 decompression, following which he
was started on oral rifampicin in November 2020, to be continued for one year.
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References
- Rifampicin and anti-hypertensive drugs in chronic kidney disease: Pharmacokinetic interactions and their clinical impact.Indian J. Nephrol. 2016; 26: 322-328
- Pregnane X Receptor Activator Rifampin Increases Blood Pressure and Stimulates Plasma Renin Activity.Clin. Pharmacol. Ther. 2020; 108: 856-865
- Resistant hypertension during antituberculosis treatment: how is rifampicin implicated?.Med. J. Malaysia. 2020; 75: 591-593
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